Director, Clinical Operations
This is a high-level leadership opportunity to head the clinical operations of a biotech firm specializing in previously undruggable GPCR targets. The role offers a unique blend of strategic oversight and hands-on execution, perfect for someone who wants to build a department while staying close to the science. With a significant salary and high organizational visibility, it is a premier role for an experienced clinical professional.
Septerna
South San Francisco, California, United States · Posted 29 April 2026
The role
Overview
The hiring side
About Septerna
Septerna is a small business working in biotechnology, based in South San Francisco, California, United States.
Biotechnology
Small
South San Francisco, California, United States
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Research SepternaWhat they need
Requirements & Skills
Key Responsibilities
- Lead the strategic planning and execution of global clinical programs across multiple therapeutic areas
- Ensure all clinical trials meet rigorous quality, regulatory, and safety standards
- Manage clinical trial budgets and resource allocation effectively
- Collaborate with senior leadership to align clinical operations with corporate development goals
- Drive continuous improvement in clinical trial methodologies and operational efficiency
Essential
- Proven leadership in operational planning for clinical programs
- Experience managing Phase I through Phase III global clinical trials
- Ability to oversee end-to-end delivery of patient-facing studies
- Expertise in maintaining compliance with regulatory and quality standards
- Track record of delivering trials on time and within budget
Preferred
- Experience in a fast-growing biotech or startup environment
- Familiarity with GPCR-focused drug discovery or small molecule programs
- Strong background in cross-functional team leadership
Key Skills
Networking
People to Know
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Perks
Benefits & perks
- Competitive annual salary ($225k - $250k)
- Opportunity to work on ground-breaking GPCR technology
- High visibility with senior leadership
- Collaborative and inclusive work environment
- Professional growth and development opportunities
- Participation in a mission-driven biotech culture
Next step
Apply now
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