Vice President, Clinical Operations, US
This executive leadership role oversees the US clinical operations for a global leader in PRAME-targeted cancer therapies. It combines high-level strategic planning with hands-on operational excellence to drive complex cell therapy trials forward. It is a unique opportunity to harmonize global clinical standards while working at the absolute cutting edge of oncology.
Immatics
Houston, Texas, United States · Posted 30 April 2026
The role
Overview
The hiring side
About Immatics
Immatics is a mid-sized employer working in biotechnology, based in Houston, Texas, United States.
Biotechnology
Medium
Houston, Texas, United States
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Requirements & Skills
Key Responsibilities
- Provide overarching strategic and operational leadership for US-based clinical activities
- Build, inspire, and manage a high-performing clinical operations department
- Ensure clinical trials meet budget, timeline, and GCP quality requirements
- Collaborate with European leadership to harmonize global standards and systems
- Proactively identify and resolve operational risks and bottlenecks
- Drive the adoption of innovative tools and agile trial execution methodologies
Essential
- Minimum of 8 years of Clinical Operations experience within the pharmaceutical or biotechnology sectors
- At least 4 years of direct line management and departmental leadership experience
- Proven track record in clinical project management
- Demonstrated ability to manage large-scale budgets and resource allocation
- Deep understanding of GCP compliance and clinical trial quality standards
- Fluency in English with exceptional verbal and written communication skills
Preferred
- Specific experience in Oncology and Cell Therapy clinical trials
- Experience working within a global or cross-functional organizational structure
- Familiarity with TCR T-cell therapies and TCR bispecifics
Key Skills
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People to Know
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Perks
Benefits & perks
- Fully remote work arrangement
- Opportunity to lead a global franchise in cancer immunotherapy
- Collaborative and diverse international work culture
- Professional development and growth opportunities
- Impactful work on life-saving cancer treatments
Next step
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